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KMID : 0363320220430030451
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Journal of Korean Oriental Internal Medicine
2022 Volume.43 No. 3 p.451 ~ p.459
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A Case Report of Chemotherapy-Induced Peripheral Neuropathy Treated with Modified Guibi-tang
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Park Su-Bin
Yoon Jee-Hyun
Kim Eun-Hye
Yoon Seong-Woo
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Abstract
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Objective: The purpose of this study was to report the effectiveness of modified Guibi-tang in a patient suffering from chemotherapy-induced peripheral neuropathy (CIPN).
Methods: A 54-year-old Korean female patient diagnosed with recurrent ovarian cancer had CIPN with other symptoms, such as anorexia, dyspepsia, insomnia, etc. She was diagnosed with Simbiyangheo and hence treated with a modified Guibi-tang. Neuropathic symptoms were assessed using a numerical rating scale (NRS) and a sensory score. Quality of life was assessed using the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group Neurotoxicity (FACT/GOG-Ntx).
Results: After 14 days of treatment, the patients showed a decrease in NRS for bilateral limb pain and improvement in other symptoms, such as general weakness, insomnia, dizziness, and headache. Quality of life also increased.
Conclusion: Modified Guibi-tang may be considered an optional treatment for CIPN if the patient is diagnosed with Simbiyangheo. Further studies are needed to confirm this finding.
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KEYWORD
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chemotherapy-induced peripheral neuropathy, Guibi-tang, cancer, herbal medicine, case report
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